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Synapses Basic question
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JacobBob
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Are the receptors that the neurotransmitters bind to the same channel proteins that open ?
I mean, in an excitatory synapse for example, do the neurotransmitters bind to Na+ channel proteins causing them to open ?
I mean, in an excitatory synapse for example, do the neurotransmitters bind to Na+ channel proteins causing them to open ?
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Bluejewel01
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Neurotransmitter binds to complemantary receptors on Na+ channels which causes them to open and Na+ ions to diffuse into post synaptic neurone and this causes a new action potential to be generated in the post synaptic membrane.
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macpatgh-Sheldon
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There are two main types of receptors: in the ionotropic receptors, what Bluejewel01 says above happens. The metabotropic ones when stimulated, being linked to G proteins, result in the activation of alpha and beta-gamma subunits, which produce a response via second messengers. Ionotropic receptors mediate responses that are much faster than those mediated by metabotropic receptors. So the answer to OP's Q is Yes for the first ones (ionotropic).
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