For example, whilst an obvious and good choice is computer animation if thats what hes interested in, he could instead study cartoon characters and paint something involving them. Or he could study different body positions and how to body moves from one position to another. He could study manga. He could make something paper mached with old comics like the beano etc. He could study how comics show movement (lines behind a person running etc)
Random idea: he could make one of those victorian toys where you spin it and the scene moves - zoetropes
For context, i chose the theme "diary" when i did my gcse. The obvious choice that most people did was to make a diary and have a craft based final project. Instead, i drew interpretations of dreams from a dream diary i kept when i was a kid, and got an A*.