Integrins Watch

shankar jan
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The wording of the 1st paragraph is a bit funny. From my own knowledge (hopefully it is correct), focal adhesion is the same thing as actin-linked junction. There are two types of extra-cellular matrix junctions : actin-linked junction and hemi-desmosome junction. The transmembrane adhesion protein for the actin-linked junction is integrin. The transmembrane adhesion protein for the hemidesmosome junction is integrin. By transmembrane adhesion protein, I mean the proteins that connect the cell to the extracellular matrix.
The cytoskeletal filament for the actin-linked junction is actin. The cytoskeletal filament for the hemi-desmosome is the intermediate filament. The cytoskeletal filaments are joined to the transmembrane adhesion proteins by some sort of anchor protein.
This is what I know from my own knowledge.
However, I don't really understand what the first paragraph is trying to explain. It seems to go off on a tangent without really explaining anything:/

The second paragraph is understandable.

I also don't understand the third paragraph.

Will be grateful if someone could share their views and thoughts.

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shankar jan
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