The correct answer is (1056C46)(44C4)/(1100C50).
The denominator is 1100C50 as this is the total number of combinations. 4% of 1100 is 44, so there are 44 defective items, and 1056 non-defective in total. There are 44C4 ways of choosing the 4 defective items we need, and 1056C46 ways to choose the remaining (non-defective) items in the sample. Hence, we multiply the two to obtain the numerator.
The answer above is incorrect, as using the Bernoulli trials method assumes that the probability of picking a defective item remains constant. However, this is not the case, as when you pick a defective item, the probability of picking another one drops. For example, at first the probability of picking a defective item is 44/1100 = 0.04, but if we do in fact pick one, then the new probability of picking another one is 43/1099.