Calculating bioavailability of a drug
4.The equation for the calculation of the dose of drug to be administered (D) is VC/F
where v is the apparent volume of drug distribution, C is the plasma concentration and F is the bioavailability of the drug. If the dose of drug administered is 1000 mg, the apparent volume of distribution is 30 litres and the plasma concentration is 2.5 mg/L. What fraction of the administered dose is available (bioavailability)?
1
0.1
0.01
0.16
0.016
The answer is 0.1 (B) but i'm struggling to work out how you get there, can anyone please explain the process in order to get 0.1 , thanks
where v is the apparent volume of drug distribution, C is the plasma concentration and F is the bioavailability of the drug. If the dose of drug administered is 1000 mg, the apparent volume of distribution is 30 litres and the plasma concentration is 2.5 mg/L. What fraction of the administered dose is available (bioavailability)?
1
0.1
0.01
0.16
0.016
The answer is 0.1 (B) but i'm struggling to work out how you get there, can anyone please explain the process in order to get 0.1 , thanks
Anyone ?
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