lane_in_pain
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Why can DNA polymerase only add nucleotides in the 5' to 3' direction? I don't understand?
thank you for your help
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EMBaguette
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(Original post by lane_in_pain)
Why can DNA polymerase only add nucleotides in the 5' to 3' direction? I don't understand?
thank you for your help
I think its because the enzyme has an active site specifically shaped only for 5'
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lane_in_pain
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(Original post by EMBaguette)
I think its because the enzyme has an active site specifically shaped only for 5'
I've since figured it out. It's actually because polymerase only catalyses the formation of the phosphodiester bond at the OH group on the 3' carbon of 2-Deoxyribose, it would be impossible to go the other way because the sugar just isn’t built like that haha. Thanks for your help! :0
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EMBaguette
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(Original post by lane_in_pain)
I've since figured it out. It's actually because polymerase only catalyses the formation of the phosphodiester bond at the OH group on the 3' carbon of 2-Deoxyribose, it would be impossible to go the other way because the sugar just isn’t built like that haha. Thanks for your help! :0
ahh well the more you know
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KATY011
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Hi can anyone send me the 2019 AS AQA PAPER 1 BIOLOGY OR GIVE ME TH E TOPICS THAT CAME UP PLEASE!
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EMBaguette
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(Original post by KATY011)
Hi can anyone send me the 2019 AS AQA PAPER 1 BIOLOGY OR GIVE ME TH E TOPICS THAT CAME UP PLEASE!
only thing I can suggest is to search on twitter with certain hashtags. The students who took the 2019 paper always talk about it after
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