Biology - AntibodiesWatch
Hi everyone. I was wandering about something. When a pathogen enters into the body, and the antigens on it stimulate an immune response, and the lymph nodes release lymphocytes which divide, before producing antibodies to counteract the pathogen and destroy it, does some of the lymphocytes that have divided remain in the lymph nodes as memory cells?
The majority of T and B lymphocytes are culled after the immune response by a "suicide" process of apoptosis; those that remain form memory cells. The persistence of these cells via their strength to survive culling is partly afforded to them by IL-15 [IL = interleukin, a type of cytokine].
Memory T and B cells require periodic stimulation by specific antigen, hence the time limit of effectiveness of vaccines.