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#1
Report Thread starter 1 year ago
#1
I have a 1000 word essay on the
pharmacokinetics and pharmacodynamics of ibuprofen ?
any ideas about this

help!!!
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JasmineAcademic
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What did you need some help with? Ideas?

in terms of PHARMACOKINETICS - I would start with the basic, Absorption, Distribution, Metabolism and Excretion.
Say how ibuprofen works through either of these steps.
How is it absorbed? can it be taken orally or through IV or injection? topically applied to skin?
How is it distributed once its in the body and by what organ? how quickly is it absorbed? is it absorbed in the stomach or the intestines? or somewhere else - this would cover its distribution.

How long does it last within the body? hours/days
How quickly does the body break down this drug?
How bioavailable is it? look at its bioavailability or its presence with blood serum. this will tell you how long it will last within the body

Look at Ibuprofen therapeutic index too, this will be how well the drug works when taking it for pain & inflammation.

For PHARMACODYNAMICS: its mechanism of action MOA
This would be more specifically what the drug does within the body to reduce pain and inflammation - so make sure to mention the inflammatory cells within the body and how ibuprofen reduces the presence of these cells.

Hope that helps and does not confuse you
Last edited by JasmineAcademic; 1 year ago
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#3
Report Thread starter 1 year ago
#3
(Original post by JasmineAcademic)
What did you need some help with? Ideas?

in terms of PHARMACOKINETICS - I would start with the basic, Absorption, Distribution, Metabolism and Excretion.
Say how ibuprofen works through either of these steps.
How is it absorbed? can it be taken orally or through IV or injection? topically applied to skin?
How is it distributed once its in the body and by what organ? how quickly is it absorbed? is it absorbed in the stomach or the intestines? or somewhere else - this would cover its distribution.

How long does it last within the body? hours/days
How quickly does the body break down this drug?
How bioavailable is it? look at its bioavailability or its presence with blood serum. this will tell you how long it will last within the body

Look at Ibuprofen therapeutic index too, this will be how well the drug works when taking it for pain & inflammation.

For PHARMACODYNAMICS: its mechanism of action MOA
This would be more specifically what the drug does within the body to reduce pain and inflammation - so make sure to mention the inflammatory cells within the body and how ibuprofen reduces the presence of these cells.

Hope that helps and does not confuse you
thanks this is super helpful ! you saved me from writers block 😂
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