idontlikeessays
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#1
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#1
Could anybody help me with this question please?

'myxopyronin inhibits bacterial RNA polymerase. Explain why the antibiotic myxopyronin can be used to treat bacterial infections in humans.'

Thank you.
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qwert7890
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#2
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#2
(Original post by idontlikeessays)
Could anybody help me with this question please?

'myxopyronin inhibits bacterial RNA polymerase. Explain why the antibiotic myxopyronin can be used to treat bacterial infections in humans.'

Thank you.
Why do you think inhibiting it would help in stopping bacterial growth? What does RNA Polymerase do?
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CaptainDuckie
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#3
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#3
Think about the RNA polymerase enzyme, and the importance of what inhibiting it has on bacterial infections.

Have you learnt it in class yet?
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qwert7890
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(Original post by CaptainDuckie)
Think about the RNA polymerase enzyme, and the importance of what inhibiting it has on bacterial infections.

Have you learnt it in class yet?
I forgot.. the title says GCSE Biology but I don’t think I’ve ever learnt about RNA polymerase at gcse?
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CaptainDuckie
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#5
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(Original post by qwert7890)
I forgot.. the title says GCSE Biology but I don’t think I’ve ever learnt about RNA polymerase at gcse?

I think a GCSE student would be able to explain this; thinking about RNA, DNA, the concepts behind it etc.

It looks like a very annoying application question.
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username5050312
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#6
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I'm doing GCSE biology and have never heard of such a question.
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idontlikeessays
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#7
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(Original post by CaptainDuckie)
Think about the RNA polymerase enzyme, and the importance of what inhibiting it has on bacterial infections.

Have you learnt it in class yet?
Ohh so would it inhibit the processes in the bacteria and prevent it from binding to the DNA?
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qwert7890
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#8
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(Original post by idontlikeessays)
Ohh so would it inhibit the processes in the bacteria and prevent it from binding to the DNA?
Yes. RNA polymerase binds to DNA and allows for the assembly of mRNA during protein synthesis.
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Jazzyfizzle21
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#9
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#9
(Original post by idontlikeessays)
Could anybody help me with this question please?

'myxopyronin inhibits bacterial RNA polymerase. Explain why the antibiotic myxopyronin can be used to treat bacterial infections in humans.'

Thank you.
Hi, there are 4 part to this question hence the 4 marks - so you will need to speak about the 4 different parts. one being the role of the RNA polymerase (see Khan academy DNA - Transcription section) two - you will need to touch upon when and how this bacteria can spread if not treated - three - you need to say how the antibiotic myxopyronin is used in humans and four - why is is being used and why we haven become resistant to it. I hope this helps! good luck
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idontlikeessays
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#10
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#10
t

(Original post by qwert7890)
Yes. RNA polymerase binds to DNA and allows for the assembly of mRNA during protein synthesis.
thank you!
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qwert7890
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#11
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#11
(Original post by idontlikeessays)
t


thank you!
You will now need to comment on the impact of RNA Polymerase inhibition on protein synthesis. Why does this inhibition stop bacterial growth?
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idontlikeessays
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#12
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(Original post by qwert7890)
You will now need to comment on the impact of RNA Polymerase inhibition on protein synthesis. Why does this inhibition stop bacterial growth?
Ummm does it prevent bacteria from being produced during the translation stage?
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qwert7890
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#13
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(Original post by idontlikeessays)
Ummm does it prevent bacteria from being produced during the translation stage?
Not exactly, because bacteria as a whole isn’t entirely protein.

However it does prevent essential proteins frombeing produced - these essential proteins are involved in the replication process of a bacteria, for example an enzyme.
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idontlikeessays
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#14
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#14
(Original post by qwert7890)
Not exactly, because bacteria as a whole isn’t entirely protein.

However it does prevent essential proteins from being produced - these essential proteins are involved in the replication process of a bacteria, for example an enzyme.
Ohhhh i think i understand now. Thank you so much for your help!
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