Allelic and Genotypic Frequencies - Genetics

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Ellie.Ginger
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How do I calculate the allele frequency of a certain allele in a population if I don't know if the population is in Hardy-Weinberg equilibrium? To add to that how do I find the genotypic frequency if we ASSUME that the population is in Hardy-Weinberg Equilibrium?
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macpatgh-Sheldon
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Hi,

Sorry that you have received no help for so long!

If the population in Q has one or more of the following features, then the use of the H-W equation will be invalid:-

a) There is selection pressure, possibly due to interaction between two factors
b) Some members of the population migrate in or out
c) There is non-random mating.

If the Hardy-W equation can be applied, you oc still need some data - given e.g. the incidence of a certain genetically transmitted disease, you just need to substitute your known value in the H-W equation to work out the required allelic frequency.

If you would like me to locate any examples for you, please PM me.

Be safe!
M [specialist biology tutor]
Last edited by macpatgh-Sheldon; 1 year ago
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