Just to add to my above comment: I learned about this when I took like twice as much as this for a few days and didn't go to the toilet once for a few days due to constipation. So I started playing around with doses and this is what I find helps me get through the day and be in the middle. I may take more if I'm in anxious situations or places I know I must try not to. But this is only one offs. You're best getting the 99p ones, rather that spending £4 for immodium. Exact same thing. But try 6-8 a day and experiment with doses. I've already discussed with numerous docs and 16mg (8 X 2mg) is fine long term, and going higher as one offs won't have any lasting effects.