Are isotope ratios in pharmaceutical drugs monitored?

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~gingkobiloba~
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#1
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may or may not be a dumb question but I genuinely can't find an answer on google, if anyone knows I'd really appreciate an answer as I'm struggling to write about this part of my EPQ
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coco:)
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Well, isotopes only have different physical properties (melting point, boiling point, etc.) from having different weights. There's no change in the chemical properties between the different isotopes so I don't think it would have too much of an effect in terms of pharmaceuticals (as long as they're all stable of course) but I'm not too sure.

Also, yes, ginkgos are awesome.
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~gingkobiloba~
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#3
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(Original post by coco:))
Well, isotopes only have different physical properties (melting point, boiling point, etc.) from having different weights. There's no change in the chemical properties between the different isotopes so I don't think it would have too much of an effect in terms of pharmaceuticals (as long as they're all stable of course) but I'm not too sure.

Also, yes, ginkgos are awesome.
I thought that too until I came upon an experiment of these maternal rats that were given different isotopes of lithium and started acting antagonistically it was so weird- one group of rats was literally cannibalising their pups and the other group was overly affectionate. But of course it is just one experiment but I have heard of some others and just thought it was a pretty interesting topic to go into but google is not telling me anything regarding the monitoring

and thanks for the username appreciation<3
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coco:)
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(Original post by ~gingkobiloba~)
I thought that too until I came upon an experiment of these maternal rats that were given different isotopes of lithium and started acting antagonistically it was so weird- one group of rats was literally cannibalising their pups and the other group was overly affectionate. But of course it is just one experiment but I have heard of some others and just thought it was a pretty interesting topic to go into but google is not telling me anything regarding the monitoring

and thanks for the username appreciation<3
Oh, that's really interesting! Maybe it's to do with the size of the rat? So not a big issue in humans. Perhaps look into veterinary pharmaceutical regulations and things? Also if you find the scientific paper for that experiment there's usually some references so you can have a look through those too and there may be more background on the effects of isotopes.
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~gingkobiloba~
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#5
(Original post by coco:))
Oh, that's really interesting! Maybe it's to do with the size of the rat? So not a big issue in humans. Perhaps look into veterinary pharmaceutical regulations and things? Also if you find the scientific paper for that experiment there's usually some references so you can have a look through those too and there may be more background on the effects of isotopes.
I'll take a look through that thanks for the advice I do hope it is to do with the size of the rat as it would be very confusing otherwise but guess I'll keep looking until I get a clearer idea
Last edited by ~gingkobiloba~; 4 months ago
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