mdbdidjdksnd
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#1
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#1
why does hiv need to use reverse transcription to make dna from rna in the host cell. Why doesn't it just have a dna strand then inject it into the host cell like normal viruses?
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Redmed_
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(Original post by mdbdidjdksnd)
why does hiv need to use reverse transcription to make dna from rna in the host cell. Why doesn't it just have a dna strand then inject it into the host cell like normal viruses?
For your information there are 4 types of viruses including:

1) ssRNA
2) ssDNA
3) dsRNA
4) dsDNA

Here, ss- single stranded , ds- double stranded

And the HIV you are asking is a ssRNA virus and all these types of viruses are also called retroviruses. Since our body is made of cells having DNA as genetic material, the virus tends to use the enzyme reverse transcriptase (which means opposite to transcription so it doesn't go from DNA --> RNA instead it goes from RNA --> DNA) to produce viral DNA that is capable of then getting incorporated into the host cell (our cells) genome. This process of reverse transcription is called Teminism which was discovered by Howard Martin Temin and David Baltimore in 1978. This theory went against the central dogma of the flow of genetic information proposed by Francis Crick (which was DNA --> RNA --> Protein) and hence came to be known as central dogma reverse.

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Last edited by Redmed_; 1 month ago
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mdbdidjdksnd
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#3
Report Thread starter 1 month ago
#3
(Original post by Redmed_)
For your information there are 4 types of viruses including:

1) ssRNA
2) ssDNA
3) dsRNA
4) dsDNA

Here, ss- single stranded , ds- double stranded

And the HIV you are asking is a ssRNA virus and all these types of viruses are also called retroviruses. Since our body is made of cells having DNA as genetic material, the virus tends to use the enzyme reverse transcriptase (which means opposite to transcription so it doesn't go from DNA --> RNA instead it goes from RNA --> DNA) to produce viral DNA that is capable of then getting incorporated into the host cell (our cells) genome. This process of reverse transcription is called Teminism which was discovered by Howard Martin Temin and David Baltimore in 1978. This theory went against the central dogma of the flow of genetic information proposed by Francis Crick (which was DNA --> RNA --> Protein) and hence came to be known as central dogma reverse.

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Views: 13
Size:  9.5 KB
Ohh okay, thank you!!
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Jpw1097
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#4
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#4
(Original post by mdbdidjdksnd)
why does hiv need to use reverse transcription to make dna from rna in the host cell. Why doesn't it just have a dna strand then inject it into the host cell like normal viruses?
It just happens to be an RNA virus.
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