Depends on the subject. Lancaster is a great international uni. If ever you want that big city buzz from time to time, its not that much for a train from Lancaster to Manchester. Theres even a direct train to London. Lancaster is a smaller city, but still has all you need when it comes to shopping, cafes, bars, restuarants and night life.
Durham you can reach the big city of Newcastle.
Its not so much the prestige of a uni. If you want that its more Oxbridge. when it comes to the rest it really does depends on the subject as some unis are better than others on that.