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    I'm not talking about if there are chromosomes extra/missing, but if the chromosome itself is damaged/sections are missing.

    What happens/what kind of diseases/syndromes can you get?
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    Damage to sections of the chromosomes are basically mutations =) they may prevent the unpacking of the chromosome for transcription or other things such as production of the wrong proteins
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    it depends how major the part of chromosome is as to what the effect is. if it is a large amount of damage on an important chromosome then this may be incompatible with life. Basically there are lots of things that could result from this.
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    Any chromosomal disease (Down, Klinfleter) can be caused by damaged chromosomes....

    E.g. Loss of Telomeres at the end, leading to Roberstonian fusions
 
 
 
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