Turn on thread page Beta
    • Thread Starter
    Offline

    11
    ReputationRep:
    Just a quick doubt angiotensin 2 if more is being made due to ACE.
    Offline

    11
    ReputationRep:
    you're question is a bit confusing. Are you asking about ACE or ACE inhibitors?
    • Thread Starter
    Offline

    11
    ReputationRep:
    well both
    Offline

    16
    ReputationRep:
    lol hmm

    Angiotensin I -> Angiotensin II

    This step is catalysed by Angiotension Converting Enzyme.

    So if you inhibit the enzyme, there will less conversion of AI to AII and that means a lower concentration of AII and AII-related effects.

    If you increase ACE, then you'll increase AII, and aldosterone production will increase.
    Offline

    1
    ReputationRep:
    (Original post by member9876)
    Just a quick doubt:

    ACE converts angiotensin 1 to angiotensin 2. Does this mean that more of angiotensin 2 is formed. Also angiotensin 2 causes an increases in aldosterone production. I don't get why ACE causes a decrease in this, why does it supress angiotensin 2 if more is being made due to ACE.
    I'm not sure I understand your question.

    ACE converts Angiotensin I into Angiotensin II. ACE Inhibitors stop this process, which brings about an overall effect of reduction in blood volume and pressure.

    If you block Angiotensin II production, you'll have a decrease in aldosterone release, which means an increase in blood volume as aldosterone increases glomerular filtration rate by causing mesangial cell relaxation and natriuresis.

    Make sense?
 
 
 
Reply
Submit reply
Turn on thread page Beta
Updated: November 17, 2008

University open days

  • Sheffield Hallam University
    City Campus Undergraduate
    Thu, 13 Dec '18
  • University of Buckingham
    Open Evening Undergraduate
    Thu, 13 Dec '18
  • University of Lincoln
    Mini Open Day at the Brayford Campus Undergraduate
    Wed, 19 Dec '18
Poll
Do you like exams?

The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

Write a reply...
Reply
Hide
Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.