Congratulations on your GCSE results! Ultimately it depends on the course you are applying for and the university you are applying to.
All universities have different entry requirements. Most top universities require anywhere between a 4-6 in GCSE Maths and English which you have exceeded. If it’s a specific subject that you are applying to eg Maths they may require a certain grade at GCSE that you must have achieved. You can check on the university website for further details on their entry requirements.
Honestly, your A-Level grades and personal statement will hold the most weight. Wishing you all the best and good luck!