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Joseph, Ting, & Butler (2019)This study found that adolescents on puberty blockers experienced a significant decline in bone density compared to peers. After two years of treatment, a notable percentage had Z-scores for bone density that were clinically concerning (below -2). Bone recovery after stopping treatment remains uncertain. Researchers in the Netherlands reported similar results, emphasizing the need to study fracture risks and long-term bone health outcomes following treatment
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The Tavistock Clinic in the UK followed adolescents on puberty blockers and noted flatlined growth trends compared to peers, raising concerns about potential impacts on final adult height
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European Journal of Endocrinology and related reports from the Tavistock Clinic (UK) - A cohort study from the Netherlands, where adolescents undergoing puberty suppression were assessed for genital development and surgical outcomes. The research showed that early initiation of puberty blockers could result in underdeveloped genitalia in males, posing challenges for gender-affirming surgeries like vaginoplasty. Limited penile tissue growth due to delayed puberty made certain procedures more complex and required alternative surgical approaches
Reply 71
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Joseph, Ting, & Butler (2019)This study found that adolescents on puberty blockers experienced a significant decline in bone density compared to peers. After two years of treatment, a notable percentage had Z-scores for bone density that were clinically concerning (below -2). Bone recovery after stopping treatment remains uncertain. Researchers in the Netherlands reported similar results, emphasizing the need to study fracture risks and long-term bone health outcomes following treatment
•
The Tavistock Clinic in the UK followed adolescents on puberty blockers and noted flatlined growth trends compared to peers, raising concerns about potential impacts on final adult height
•
European Journal of Endocrinology and related reports from the Tavistock Clinic (UK) - A cohort study from the Netherlands, where adolescents undergoing puberty suppression were assessed for genital development and surgical outcomes. The research showed that early initiation of puberty blockers could result in underdeveloped genitalia in males, posing challenges for gender-affirming surgeries like vaginoplasty. Limited penile tissue growth due to delayed puberty made certain procedures more complex and required alternative surgical approaches
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