LSE

Hi everyone, I was wondering if people could offer me some guidance. I am predicted 4 A*s with GCSEs of 99999887777 and despite having competitive PS to apply, I don't really know if there's hope for me to get in. I got a 7 in maths and underperformed due to personal circumstances involving family and was just wondering if they even consider these circumstances in application if they're referenced. I guess I've seen so many students will 12 9s applying for courses at LSE like Econ and joint Eco degrees that I would like to know if I should even consider LSE. Thank you!