Hi, entering imperial this year myself, so I don’t have any experience, but I did some research with all of those questionaries being sent to us. My course is F124 (Chemistry with Medicinal Chemistry MSci), so the choice was already made by past me, but I have looked at all options out of interest.
As was said before me, you can take a language as a horizon (which are optional courses, and can only give you extra credits, that do not count towards you degree credits). But if you want to enter at a level above beginner, you need a proof of our level of language (like GCSE, A-level, IB, or language test, you can find which exactly on their website).
Overview for Medicinal chemistry 1 said that this course will be focused (as far as I understand) on organic aspects of chemistry and cellular aspects of biology. So if you enjoyed that kind of stuff during a-level, maybe you should consider it. If you didn’t, then I’d recommend against taking this course.
As for Physics and Math 1, technically doing a-level physics is not a requirement to enter, so it’s meant that student who didn’t do it should be capable of completing this course. Obviously it will be easier for those, who did physics before, but further math should also be an okay base.
And I definitely recommend reading through all the information they give on the website (might take a bit of searching) and in the welcome booklet they sent everyone via email, if you haven’t done so before.
To summarize, I recommend getting as much info on course details as you can, and then comparing it to the topics you enjoyed or didn’t enjoy during a-levels. And then choose the one that has the most of what you enjoyed/where good at. Obviously university course will have much more topics, than a-levels had, so there still will be some wondering about what you will you enjoy more, as you have never done anything like that. That’s why I would try to judge based on adjacent experiences I had (the most similar stuff I learned before).
Hope that helps! (and sorry for being a yapper?)