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Original post by weetabix_muncher
I am in my first year of sixth form. I am taking maths, physics and chemistry in school, but because my school don't offer computer science, and I really want a cs A Level, I am self studying that alongside the A Levels. I will try to post everyday on what I have done for the day. If any of you have any exam questions, or questions about my subjects or just some tips, feel free to post.
For GCSEs, I got...
Bio - 7
Chem - 7
Phy - 7
Lang - 6
Lit - 7
Maths - 8
CS - 8
Geo - 6
RE - 9

classy
crap. I keep forgetting to post here. Basically the past few days, I haven't doe much, just paying attention in class and doing any hmwk. I need to start revising properly bc the lessons are getting hard quickly and if i dont start soon, i will fall behind. I havent gone school today bc i am ill, so i asked my physics and chemistry teacher to email me what they are doing in lesson today. I wouldnt have had maths today anyways
Physics and maths are going well so far, but chemistry is already forcing me to forget/ignore things I learned in GCSE
I also need to make a start on computer science, which i will be self studying. I might do that now after i have breakfast
For chem, I need to look at mass spectrometry and the difference between the 2 types of ionisation, before doing exam questions on it. Physics work still hasnt been recieved.
Original post by weetabix_muncher
Physics and maths are going well so far, but chemistry is already forcing me to forget/ignore things I learned in GCSE

bruh same in forgot what a ion was for like a full 10 minutes
Original post by animazddhdnm
bruh same in forgot what a ion was for like a full 10 minutes

prsom. At teh beginning of 6th form, we had to recall grade 7 mathts, and i was so confused for half an hour, before it all came back to me
Original post by weetabix_muncher
prsom. At teh beginning of 6th form, we had to recall grade 7 mathts, and i was so confused for half an hour, before it all came back to me

tbh I think it joust cuz we having looked at it at a long time cuz I can still duo like challenging calcoulation and get it right I just don't how its right and why and how I even got the write answer for it in the first plac. that the thing about a level you actually have know how to explain you answer and not just half guess and happen to get it right. with sucks but ithink im getting I finished mass spec btw if you need any help let me know also my exam Brad is edexel
Original post by animazddhdnm
tbh I think it joust cuz we having looked at it at a long time cuz I can still duo like challenging calcoulation and get it right I just don't how its right and why and how I even got the write answer for it in the first plac. that the thing about a level you actually have know how to explain you answer and not just half guess and happen to get it right. with sucks but ithink im getting I finished mass spec btw if you need any help let me know also my exam Brad is edexel

im doing aqa but could u still explain it?
Original post by weetabix_muncher
im doing aqa but could u still explain it?

umm I suck at exlainig but illl try
danm I wish you could do audio messages on her car now I have to type it
wait do you want brief explanation of more in detail
Original post by weetabix_muncher
im doing aqa but could u still explain it?

ok so this is I how ive written it in my notes

Mass spectrometry enables chemists to measure atoms and molcules by ionising them and analysing their movement in electric and magnetic fields. Positive ions, formed by electron bombardment, are accelerated and deflected, depending on their mass-to-charge ratio. By adjusting the fields, ions of different masses are dtected The resulting mass spectrum provides insight into the molecular structure, with peaks representing the ionised molecule and its fragmnts. The method is highly sensitive, and high-resolution spectrometers allow for precise molecular formula determination. GCMS combined gas chromatography with mass spectrometry for advanced analysis.

hope this helps
I also did this essay on it you don't need to know is for your exam board I think I think but still could help you apply it to real life situations.

Precision Under Pressure: The Role of Mass Spectrometry in Anesthesia Monitoring
Introduction
Mass spectrometry (MS) plays a vital role in medical applications, especially in monitoring patients under anaesthesia. By analysing exhaled gases, MS helps anesthesiologists track the levels of anaesthetic agents, respiratory gases like carbon dioxide, and other metabolic by-products. The precision and sensitivity of MS make it ideal for real-time monitoring, enabling rapid adjustments to anaesthesia, drug dosing, and ventilation. This minimises risks and ensures patient safety during surgery by offering insights into the body’s physiological state, drug metaolism, and respiratory function.

Mass spectrometry (MS) is used to monitor a patients breathing during anaesthesia by analysing exhaled gases, specifically volatile anaesthetic agents (e.g., isoflurane) and respiratory by-products like carbon dioxide (CO2). The process involves:
Gas Sampling: A small portion of the exhaled breath is introduced into the MS system.

1.

Ionisation: Molecules in the gas are ionised to form chared particles.

2.

Separation: The ions are separated based on their mass-to-charge ratio, allowing for the identification of gases and anesthetic agents.

3.

Monitoring: By tracking the concentration of anaesthetic gases and respiratory gases like CO2, MS provides real-time data on a patent’s respiratory and metabolic state.

1. Drug Monitoring:
Mass spectrometry is vital in monitoring drug levels especially during anaesthesia, to ensure proper dosing of anaesthetic agents and sedatives. By measuring blood or breath samples, MS can provide real-time information about the concentation of drugs like isoflurane, propofol, or opioids in a patient’s system. This helps anesthesiologists tailor the anaesthesia dose to the individual, minimising the risk of overdose or underdose, which could either lead to prolonged sedation or the patient waking up during surgery.
2. Detecting Metabolic Changes:
Metabolic markers in breath or blood provide insight into the body’s response to anaesthesia. MS can detect changes in CO2 levels, lactate, or glucose metabolites, indicating how orgns are functioning during surgery. For example, abnormaly high CO2 in exhaled breath may signal respiratory failue, while shifts in blood metabolites could indicate stress on organs like the liver or kidneys. MS helps identify these subtle changes, allowing doctors to intervene early and prevent complications such as acidosis or organ damage.
3. Real-time Feedback:
Mass spectrometry offers rapid, near-instantaneous analysis, which is crucial for surgeries. By continuously monitoring gases and drug levels, MS allows anaesthetists to adjust the administration of anaesthesia or oxygen supply dynmically. Real-time data on exhaled anaesthetic agents (like halothane or sevoflurane) and respiratory gases sch as O2 and CO2 help ensure the patient remains stable throughout the operation, reducing the risk of anaesthesia-related complications such as hypoxia or awareness under anaesthesia.
This real-time monitring enhances patient safety by ensuring approriate ventilation gas exchange, and drug administration during surgical procedures.
Why it's used:

Anaesthetic Levels: The amount of anaesthetic in the breath indicates whether the patient is receiving an adequate dose.

CO2 Levels: Abnormal CO2 levels may indicate respirtory issues, alerting anaesthetists to adjust ventilation or medication.

MS is particularly valued for its sensitivity and acuracy, allowing for precise control over anaesthesia and better patient outcomes.
Additional use in moterring brething
Mass spectrometry is used in monitoring brething by analysing the composition of exhaled gases. This technique can detect trace amounts of volatile organic compounds (VOCs) in breath, which are biomarkers for various physiological and pathological conditions. For example, specific VOCs in exhaled breath can indicate metaboic processes or disease states like astha, lung infections, or cancer. By identifying and measuring these compounds mass spectrometry provides a non-invasive method to monitor respiratory health and detect early signs of illness.
Conclusion
In conclusion, mass spectrometry is a crucial tool in modern anaesthesia, providing precise and real-time monitoring of anaesthetic agents and metabolic markers. Its ability to measure drug concentrations, detect changes in respiratory gases, and analyse metabolic by-products ensures that anaesthesia is adminisered safely and effectively.This real-time feedback enables healthcare professionals to respond quickly to any changes in a patient’s condition during surgery, minimising risks and improving outcomes. As technology advances the role of MS in anaesthesia and broader medical applications will continue to expand.
Original post by animazddhdnm
ok so this is I how ive written it in my notes
Mass spectrometry enables chemists to measure atoms and molcules by ionising them and analysing their movement in electric and magnetic fields. Positive ions, formed by electron bombardment, are accelerated and deflected, depending on their mass-to-charge ratio. By adjusting the fields, ions of different masses are dtected The resulting mass spectrum provides insight into the molecular structure, with peaks representing the ionised molecule and its fragmnts. The method is highly sensitive, and high-resolution spectrometers allow for precise molecular formula determination. GCMS combined gas chromatography with mass spectrometry for advanced analysis.
hope this helps

Thannks but I might just watch a few videos on it. I still dont understand it... sorry
Original post by weetabix_muncher
Thannks but I might just watch a few videos on it. I still dont understand it... sorry

no it it ok wait Ill give you the link to the video that help me understand it it ia bit old bt I good https://www.youtube.com/watch?v=J-wao0O0_qM
Original post by weetabix_muncher
For chem, I need to look at mass spectrometry and the difference between the 2 types of ionisation, before doing exam questions on it. Physics work still hasnt been recieved.

https://www.savemyexams.com/a-level/chemistry/aqa/17/revision-notes/1-physical-chemistry/1-1-atomic-structure/1-1-3-time-of-flight-mass-spectrometry/
Its been another uninventful day full of procrastination. I seriously need help to not porcrastinate
Original post by weetabix_muncher
Its been another uninventful day full of procrastination. I seriously need help to not porcrastinate

pomodoro timers... that's how i roll.
34:32 - irish (pomofocus.io)
as you can see i've mislabelled what im supposed to be doing. but my point remains.
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(edited 2 weeks ago)
Original post by SWAN 2.0
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prsom

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