Reply 1
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It may be that the increased concordance rates in the Gottesman study were due to the increased chance of sharing the same environment as the person with schizophrenia. For example, identical twins share the same environment (and may be treated similarly), whereas first cousins would not. This means that it can’t be concluded that genetics has caused schizophrenia.
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As identical twins share 100% of their genes, it would be expected that the concordance rate for schizophrenia would be 100% if it was purely genetic. As it is only around 50%, this suggests other influences are playing a part.
Reply 2
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It may be that the increased concordance rates in the Gottesman study were due to the increased chance of sharing the same environment as the person with schizophrenia. For example, identical twins share the same environment (and may be treated similarly), whereas first cousins would not. This means that it can’t be concluded that genetics has caused schizophrenia.
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As identical twins share 100% of their genes, it would be expected that the concordance rate for schizophrenia would be 100% if it was purely genetic. As it is only around 50%, this suggests other influences are playing a part.
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