So if ethanol dissolves lipids/phospholipids, then why doesn't drinking alcohol or applying acetone to your nails basically dissolve you??
Ethanol and acetone are powerful chemicals that can disrupt lipid and/or phospholipid structures, but our body's advanced barrier system of skin and mucous membranes responds quickly to prevent this breakdown. In addition, our body's impressive ability to process and eliminate these substances helps to mitigate their effects. This natural defence mechanism acts as a shield to ensure that these substances don't compromise the integrity of our cells. However, when misused in high concentrations or prolonged exposure, ethanol and acetone can cause serious damage. Caution: Repeated contact with acetone may cause skin dryness or cracking, while ethanol may cause severe eye irritation.