Biology question URGENT help please
Hi, please could I have some help on this question? I’m really confused why oxygen demand is lower in cancer cells, surely it should be higher because they have higher metabolic requirements?
Here is the question: https://ibb.co/gVRJ3nw
Thank you!
Here is the question: https://ibb.co/gVRJ3nw
Thank you!
Reply 1
Original post
by anonymous56754Hi, please could I have some help on this question? I’m really confused why oxygen demand is lower in cancer cells, surely it should be higher because they have higher metabolic requirements?
Here is the question: https://ibb.co/gVRJ3nw
Thank you!
Here is the question: https://ibb.co/gVRJ3nw
Thank you!
Hello!
I don't know if you've studied the Warburg effect, which says that cancer cells need more glucose than healthy cells because they use glycolysis to produce ATP in the absence of oxygen, which is a hallmark of anaerobic respiration.
The body converts glucose to make oxidative phosphorylation work better. Oxidative phosphorylation depends on cancer cells preferring to use glucose, so cancer cells require less oxygen.
Give a look here: https://en.wikipedia.org/wiki/Warburg_effect_(oncology)
Bye,
Sandro
Reply 2
13
Original post
by NitrotolueneHello!
I don't know if you've studied the Warburg effect, which says that cancer cells need more glucose than healthy cells because they use glycolysis to make ATP in the presence of oxygen. The body converts glucose to make oxidative phosphorylation work better. Oxidative phosphorylation depends on cancer cells preferring to use glucose, so cancer cells require less oxygen.
Give a look here: https://en.wikipedia.org/wiki/Warburg_effect_(oncology)
Bye,
Sandro
I don't know if you've studied the Warburg effect, which says that cancer cells need more glucose than healthy cells because they use glycolysis to make ATP in the presence of oxygen. The body converts glucose to make oxidative phosphorylation work better. Oxidative phosphorylation depends on cancer cells preferring to use glucose, so cancer cells require less oxygen.
Give a look here: https://en.wikipedia.org/wiki/Warburg_effect_(oncology)
Bye,
Sandro
sorry, when you said "cancer cells need more glucose than healthy cells because they use glycolysis to make ATP in the presence of oxygen." did you mean absence of oxygen because ATP is produced only in glycolysis when there is anaerobic respiration?
Reply 3
Original post
by anonymous56754sorry, when you said "cancer cells need more glucose than healthy cells because they use glycolysis to make ATP in the presence of oxygen." did you mean absence of oxygen because ATP is produced only in glycolysis when there is anaerobic respiration?
You are absolutely right. I apologise for the mistake. Cancer cells use glycolysis to produce ATP in the absence of oxygen, not in the presence of oxygen.
So, the correct statement is as follows: cancer cells need more glucose than healthy cells because they use glycolysis to produce ATP in the absence of oxygen, which is a hallmark of anaerobic respiration.
See reply #1
Bye,
Sandro
(edited 1 year ago)
Reply 4
13
Original post
by NitrotolueneHello!
I don't know if you've studied the Warburg effect, which says that cancer cells need more glucose than healthy cells because they use glycolysis to produce ATP in the absence of oxygen, which is a hallmark of anaerobic respiration."cancer cells need more glucose than healthy cells because they use glycolysis to make ATP in the presence of oxygen". See reply #3.
The body converts glucose to make oxidative phosphorylation work better. Oxidative phosphorylation depends on cancer cells preferring to use glucose, so cancer cells require less oxygen.
Give a look here: https://en.wikipedia.org/wiki/Warburg_effect_(oncology)
Bye,
Sandro
I don't know if you've studied the Warburg effect, which says that cancer cells need more glucose than healthy cells because they use glycolysis to produce ATP in the absence of oxygen, which is a hallmark of anaerobic respiration.
The body converts glucose to make oxidative phosphorylation work better. Oxidative phosphorylation depends on cancer cells preferring to use glucose, so cancer cells require less oxygen.
Give a look here: https://en.wikipedia.org/wiki/Warburg_effect_(oncology)
Bye,
Sandro
Hi, thanks for clarifying, so essentially cancer cells need more glucose because they mainly rely on glycolysis for ATP and therefore also require less oxygen? Just a follow up question, why is it that they rely on glycolysis only, in other words, why is anaerobic respiration taking place in cancer cells if there is probably enough oxygen (as for other body cells) or are the cells competing so there is less oxygen available? Thank you!
Reply 5
Original post
by anonymous56754Hi, thanks for clarifying, so essentially cancer cells need more glucose because they mainly rely on glycolysis for ATP and therefore also require less oxygen? Just a follow up question, why is it that they rely on glycolysis only, in other words, why is anaerobic respiration taking place in cancer cells if there is probably enough oxygen (as for other body cells) or are the cells competing so there is less oxygen available? Thank you!
In total, you asked four questions, and each of them very accurately describes important aspects of cancer cell metabolism.
It sounds paradoxical, but your questions already contained the answers.
Well done anonymous56754!
Bye,
Benzene
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