Do you have to know the mechanism for acyl chloride + amine?

For OCR A level Chemistry to do you have to know the nucleophilic substitution mechanism for the reaction of acyl chloride and amine to form an amide?
What are all the mechanisms we should know for OCR A level chemistry?

Reply 1

TypicalNerd

18

Original post by iamkiri

For OCR A level Chemistry to do you have to know the nucleophilic substitution mechanism for the reaction of acyl chloride and amine to form an amide?
What are all the mechanisms we should know for OCR A level chemistry?

For OCR, no. Only AQA requires nucleophilic addition-elimination

OCR A only really requires electrophilic addition, nucleophilic substitution (SN2), electrophilic substitution and nucleophilic addition if memory serves.

(edited 2 months ago)

Reply 2

Pigster

20

Original post by iamkiri

For OCR A level Chemistry to do you have to know the nucleophilic substitution mechanism for the reaction of acyl chloride and amine to form an amide?
What are all the mechanisms we should know for OCR A level chemistry?

You aren't expected to know the mechanism (TN's memory serves correctly), but you might be given a partially completed mechanism for your reaction as a scaffold and asked to complete it.

Do you have to know the mechanism for acyl chloride + amine?

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