I need some help quite urgently, I've been trying to come up with some sort of 'reasonable' answers to these:
i've worked out 7a) i) properly so far, but has anyone got any ideas/hints towards some sort of answer I can write for any of the rest?
I also think a sulfur ylid can be used to make the epoxide for ii), but i'm not sure about making the ring
I'm actually diabolically bad at retro style questions.
Degree level Chemistry - anyone good at retrosynthesis?? Watch
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Last edited by Salain; 05-08-2009 at 13:02.
- 05-08-2009 12:50
- 05-08-2009 15:56
for 7a)ii) consider using possibly allyl cuprate to add 1,4 - then add HBr across the double bond to give the bromide - then use the enol(ate) to do an Sn2 to displace the Br and form the ring - finally the sulfur ylide as you've suggested.Last edited by EierVonSatan; 05-08-2009 at 16:13.