Turn on thread page Beta

Degree level Chemistry - anyone good at retrosynthesis?? watch

    • Thread Starter

    I need some help quite urgently, I've been trying to come up with some sort of 'reasonable' answers to these:


    i've worked out 7a) i) properly so far, but has anyone got any ideas/hints towards some sort of answer I can write for any of the rest?
    I also think a sulfur ylid can be used to make the epoxide for ii), but i'm not sure about making the ring

    I'm actually diabolically bad at retro style questions.

    for 7a)ii) consider using possibly allyl cuprate to add 1,4 - then add HBr across the double bond to give the bromide - then use the enol(ate) to do an Sn2 to displace the Br and form the ring - finally the sulfur ylide as you've suggested.
Submit reply
Turn on thread page Beta
Updated: August 5, 2009

University open days

  1. University of Bradford
    University-wide Postgraduate
    Wed, 25 Jul '18
  2. University of Buckingham
    Psychology Taster Tutorial Undergraduate
    Wed, 25 Jul '18
  3. Bournemouth University
    Clearing Campus Visit Undergraduate
    Wed, 1 Aug '18
How are you feeling in the run-up to Results Day 2018?

The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

Write a reply...
Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.