Chemistry organic synthesis

euphoricrora

Can someone help me work out what 28 and 29 are ( I think that 26 and 27 are water and phenol with No2)

Reply 1

euphoricrora

Here's the question :smile:

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Reply 2

user1034723

hi 26 and 27 is correct
but im unsure on 28

29 is hcl because its always the product in friedal crafts acylation

Reply 3

ghostyblop

Hi,

I've outlined a way to attempt this synthesis below, I'm not sure whether you're doing a levels or not so I included the directing effects of the phenol groups to help show why the NO2 groups add to the C-2 and C-4. If you are still doing A Levels *Ignore this part* you just need to know that the alcohol is an electron donating group so will add the substituent to carbons 2 and 4.

This synthesis starts with a nitration of benzene, where you'll get a mixture of products, followed by a nucleophilic addition-elimination reaction:

(sorry I've just seen I did the first equations wrong lol its late haha... you should form [HNO3]+ I wrote [HNO2]+)

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