I'm a Biology student doing a Pharmacology module and I'm not too sure where to post this question but thought the Chemistry forum fitted it the best.
What does non-specific binding of a ligand show? That is besides specific binding as specific binding is (total bound-non-specific).
The question in my assignment is : What does the non-specific binding tell you about epibatidine (that's the ligand). And I can't think of anything more than it tells you than the specific binding of the ligand to the receptor. Or is that the only thing. It just sounds so blindingly obvious.
I'm a Biology student doing a Pharmacology module and I'm not too sure where to post this question but thought the Chemistry forum fitted it the best.
What does non-specific binding of a ligand show? That is besides specific binding as specific binding is (total bound-non-specific).
The question in my assignment is : What does the non-specific binding tell you about epibatidine (that's the ligand). And I can't think of anything more than it tells you than the specific binding of the ligand to the receptor. Or is that the only thing. It just sounds so blindingly obvious.
Think about proportions of ligand to substrate. Photometry is a possibility. Also non specific to me would suggest a closely related class of receptors.