I would not want to predict just know all of the stuff in the book. As you can see on most of the papers they have asked about ex situ. Might be in terms of seed banks or captive breeding.

Reply 391

username854791

OP

14

What actually causes the damage to the epithelial of the artery wall to allow the plaque to deposit?

Reply 392

Unsworth

14

Original post by Future_Dr

What actually causes the damage to the epithelial of the artery wall to allow the plaque to deposit?

Firstly, it's the endothelium, not epithelial, and that damage is cause by carbon monoxide and by high blood pressure.

Secondly, plaque isn't deposited. Cholesterol and LDL's are what are deposited, forming an atheroma. A plaque is only when the atheroma breaks through the endothelium lining and sticks out into the lumen of the artery.

Reply 393

Salmonidae

1

Original post by Future_Dr

What actually causes the damage to the epithelial of the artery wall to allow the plaque to deposit?

High blood pressure often caused by a high salt diet

Reply 394

username854791

OP

14

Does angina, mycocardial infarction and cardiac arrest and conary thrombosis all come under Coronary Heart Disease?

Reply 395

Salmonidae

1

Original post by Future_Dr

Does angina, mycocardial infarction and cardiac arrest and conary thrombosis all come under Coronary Heart Disease?

Yes, although it's worth bearing in mind that coronary thrombosis and mycocardial infarction lead to cardiac arrest, not the other way around.

Reply 396

username854791

OP

14

Original post by Unsworth

Firstly, it's the endothelium, not epithelial, and that damage is cause by carbon monoxide and by high blood pressure.

Secondly, plaque isn't deposited. Cholesterol and LDL's are what are deposited, forming an atheroma. A plaque is only when the atheroma breaks through the endothelium lining and sticks out into the lumen of the artery.

Can you please tell me in detail what is a plaque, atheroma, and athermateous plaque. Sorry but it doesn't really state the differences in my notes so I assumes that they were the same. Also I thought that Cholestrol were due to the LDLs as they were carried that way. Do you get LDLs and Cholestrol seperate?

(edited 11 years ago)

Reply 397

mathsclown

7

Hoping these topics come up:
Nucleic acids
Haemoglobin vs collagen
Artifical selection
Immune system
Smoking
And any of the easy stuff from biodiversity lol :P

Reply 398

Unsworth

14

Original post by Future_Dr

Can you please tell me in detail what is a plaque, atheroma, and athermateous plaque. Sorry but it doesn't really state the differences so I assumes that they were the same.

Ok, so an atheroma is basically the deposits of fatty substances, cholesterol, low density lipoproteins, dead cells, platelets and fibres.

An atheroma is caused by atherosclerosis. This is happens by carbon monoxide and/or high blood pressure causing damage to the endothelium (inner lining) of the artery. This damage to the artery encourages the deposition of those fatty substances, cholesterol, LDL's etc.

The continuous build up of these deposits under the endothelium of the artery may cause the atheroma to build up and stick out, into the lumen of the artery - this is called a plaque.

A plaque further reduces blood flow, as the lumen is smaller, so blood pressure increases further. The membrane which covers the plaque can get damaged due to the high blood pressure, this leaves the fatty deposits exposed. Nicotine in cigarette smoke causes the platelets and red blood cells in the blood to become more sticky, and so these can get can stuck to the exposed fatty deposits on the plaque. This is called thrombosis.

Thrombosis can also lead to a thrombus (a blood clot) which can be broken off and clog a narrower artery, which will stop blood flow to that artery and may lead to a stroke.

I have never heard of an athermateous plaque before though, so I can't help you there, I doubt you need to know what it is either.

Hope that helped a bit!

Reply 399

Salmonidae

1

Original post by Future_Dr

Can you please tell me in detail what is a plaque, atheroma, and athermateous plaque. Sorry but it doesn't really state the differences in my notes so I assumes that they were the same. Also I thought that Cholestrol were due to the LDLs as they were carried that way. Do you get LDLs and Cholestrol seperate?

They all do mean the same thing I believe, and they lead to the condition Artheriosclerosis.

OCR Biology F212 (Molecules, Biodiversity, Food and Health)- 21st May 2012

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