Biology help needed please!

wigman15

1

Hey!

How do lymphocytes get to the sites of infection from the lymph nodes?

Thanks

Reply 1

GH

13

wigman15

Hey!

How do lymphocytes get to the sites of infection from the lymph nodes?

Thanks

They utilize specialized surface proteins and carbohydrate entities called adhesion molecules for trafficking through the host. These adhesion molecules recognize specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs allowing them to bind and cross through the endothelial cell barriers.

Reply 2

wigman15

OP

1

2 2776

They utilize specialized surface proteins and carbohydrate entities called adhesion molecules for trafficking through the host. These adhesion molecules recognize specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs allowing them to bind and cross through the endothelial cell barriers.

Thank you very much for your help. Unfortunately, I do not understand most of that as I am an AS student and haven't done much detail about lymphocytes at school.

Reply 3

GH

13

wigman15

Thank you very much for your help. Unfortunately, I do not understand most of that as I am an AS student and haven't done much detail about lymphocytes at school.

Same here. You can surely understand some of it, ie carrier proteins etc...

Reply 4

wigman15

OP

1

2 2776

Same here. You can surely understand some of it, ie carrier proteins etc...

I understand that bit, but what does this mean "specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs"?

Reply 5

GH

13

wigman15

I understand that bit, but what does this mean "specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs"?

Ligands are like water ligands on berilium. Similar to glycoproteins in shape and function.

Endothelial cells are cells in the inside of the blood vessel

Vasculature-mass transport system of body, ie blood vessel

2ndry lymphoid organs = control the quality of immune responses. There are Differences among the various lymphatic tissues, this is the secondary one