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Facilitated diffusion questions

I'm a little bit confused about :

The difference between a gated protein channel and a non - gated protein channel? Do both protein channels allow specific molecules to go through them?

What type of molecules will go through a gated protein channel? And what type of molecules will go through a non gated protein channel?

Can water pass through the phospholipid bi-layer gradually, or will it always have to go through a protein channel?

Any knowledge about these questions will be very helpful, thanks.
Original post by MeZala
I'm a little bit confused about :

The difference between a gated protein channel and a non - gated protein channel? Do both protein channels allow specific molecules to go through them?

What type of molecules will go through a gated protein channel? And what type of molecules will go through a non gated protein channel?

Can water pass through the phospholipid bi-layer gradually, or will it always have to go through a protein channel?

Any knowledge about these questions will be very helpful, thanks.


In normal diffusion, gases like carbon dioxide and oxygen are allowed to diffuce through the phospholipid bilayers. How ever some molecules like C6-H12-O6, charged ions, and large molecules would have an hard time diffusing through cell membranes so the cell surface has protein receptor to detect useful large molecules and also have Glycolipids and Glycoproteins polymers which acts as receptors which help bind some molecules. Intrinsic proteins like Protein Channels and Carrier proteins aid in the process of 'Facilitated Diffusion' where large molecules can pass through the cell membrane. Facilitated diffusion is an form of Passive transport because it does not use energy. Carrier proteins change shape to allow these molecules to go through. Active transport also uses carrier proteins but uses energy to allow small and large molecules to travel against it's concentration gradient. It uses energy in the form of ATP which hydrolyses to become ADP+ (Pi) (An Phosphate Group).
In bulk transports, cell membranes changes structure to allow endocytosis and pinocytosis is an form of endocytosis which allows substances like water to be engulfed in the cell.

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