If you don't want to get an uber then look up reliable taxi firms before you go and ring one and get a taxi if there are three of you. Check the name of the person who will be picking you up and check this before you get in the taxi.
Same applies to an uber. Take a photo of the uber number plate as he arrives. You can send an uber link to someone whilst in the uber so they can trace you and mention this to a friend in the uber so that the uber driver hears. As said above, call someone whilst in the uber and talk about the fact you are in one and the route you are taking etc.
Don't go to the toilet alone.
Watch your drinks very carefully all the time.
Don't accept drinks from anyone.
You can get those drink covers in some places or take your own to help avoid spiking.
Take some emergency cash and keep it separate to your bag/phone in case either is stolen or lost and you get accidentally separated from friends.
Take some numbers of people you can call for help and reliable taxi firms and keep them separate to your bag and phone in case you need them.
Obviously don't leave your stuff unattended.
Never separate from friends. If one of you has to leave a club or is refused entry, at least one of you must go with that person. Agree this before you go and agree who is willing to do this.
Safety in numbers.
Don't appear drunk. If you do the bouncers may chuck you out of the club or refuse you entry and they are not always nice people.
One of you at least needs to stay relatively sober.
I have a daughter who goes clubbing sometimes in what I think are rough clubs in the city centre and she does all of this.
Have great fun clubbing!