The Student Room Group

Proof that any complete cure for any cancer would be "suppressed"?

A recent story a couple of days ago:

http://www.thelocal.de/society/20121118-46239.html

German cancer experts are warning of a looming shortage of one of the most widely used drugs to treat the disease because pharmaceutical companies say it is not financially worth their while to make it any more.

Fluorouracil, also known as 5-FU, is a chemotherapy agent used to treat bowel and breast cancer. It is one of the most commonly prescribed drugs for cancer patients worldwide.

But many of Germany's top providers have stopped making the drug because it is not as profitable as other, more expensive ones. Of the six main companies which supplied 5-FU to pharmacies across the country, only one - Medac - is still is doing so, Der Spiegel magazine said on Sunday.


What do you think about this? Can we infer from this that the road to creating a complete cure for specific types of cancers etc will be deliberately made very difficult in order to safeguard "profit"? Or is this overreacting?

Any thoughts?
Reply 1
Original post by HomoSapiensSap
A recent story a couple of days ago:

http://www.thelocal.de/society/20121118-46239.html



What do you think about this? Can we infer from this that the road to creating a complete cure for specific types of cancers etc will be deliberately made very difficult in order to safeguard "profit"? Or is this overreacting?

Any thoughts?


As a Pharmacy student, I think the use of 5-Fluorouracil in developed nations will cease to be used, all be it rarely, over the next few years. Newer drugs have now replaced a lot of its use. Also, surely if there is only 1 company left making it in Germany, they will have more business as the others have dropped off?
Original post by degreeny
As a Pharmacy student, I think the use of 5-Fluorouracil in developed nations will cease to be used, all be it rarely, over the next few years. Newer drugs have now replaced a lot of its use. Also, surely if there is only 1 company left making it in Germany, they will have more business as the others have dropped off?


This is the truth.

The implications aren't of the drug being phased out for profits, its the case that newer and more effective drugs have been made.

The article is a bit fear-mongering. Xeloda has become the most likely successor to the popularised 5FU, which contains the benefits of 5FU amongst numerous other components.

This solitary article doesn't expand on the situation more. If it was a complete freezing of the FU from ALL products, that would be a different case, but I get the impression it's a poorly researched article which doesn't count drugs that contain 5FU as being the same.
(edited 11 years ago)
Reply 3
If a pharmaceutical company was able to produce a pill that cured a specific form of cancer in six doses, they would be shooting themselves in the foot by not producing and selling it. Think of all the man-hours of care the patient would otherwise have to receive. They could charge what they wanted for that pill.
Original post by TheBugler
If a pharmaceutical company was able to produce a pill that cured a specific form of cancer in six doses, they would be shooting themselves in the foot by not producing and selling it. Think of all the man-hours of care the patient would otherwise have to receive. They could charge what they wanted for that pill.


But a cure would be precisely what large pharmaceutical companies wouldn't want - it would eventually put them out of business as it now makes the industry a short-term one. Consider this situation to put it into perspective: imagine if independent research scientists came up with a cure for a specific form of cancer, but instead of selling it for colossal amounts, they simply gave it free (to the NHS or individuals). This would put many out business and greatly threaten companies in that sector.
Reply 5
Original post by HomoSapiensSap
But a cure would be precisely what large pharmaceutical companies wouldn't want - it would eventually put them out of business as it now makes the industry a short-term one. Consider this situation to put it into perspective: imagine if independent research scientists came up with a cure for a specific form of cancer, but instead of selling it for colossal amounts, they simply gave it free (to the NHS or individuals). This would put many out business and greatly threaten companies in that sector.


But if such a cure is even possible then the industry is a short-term one whether they like it or not. Anyone with a modicum of sense would be the first to make the pill, charge pretty much whatever price they want for it, and then take their profits and invest them elsewhere.
you say proof but you mean bull****.
Reply 7
Original post by HomoSapiensSap
But a cure would be precisely what large pharmaceutical companies wouldn't want - it would eventually put them out of business as it now makes the industry a short-term one. Consider this situation to put it into perspective: imagine if independent research scientists came up with a cure for a specific form of cancer, but instead of selling it for colossal amounts, they simply gave it free (to the NHS or individuals). This would put many out business and greatly threaten companies in that sector.


A cure for a specific form of cancer wouldn't prevent people from developing it though, people will always develop cancer. If independent research scientists did develop a cure for one form, pharmaceutical companies would just invest more research and money into possible cures for other forms as well as tinkering with the newly discovered drug which could potentially treat many more form with a few changes. If anything those independent researchers could end up making big pharmaceutical companies even more money
Reply 8
But a cure would be precisely what large pharmaceutical companies wouldn't want - it would eventually put them out of business as it now makes the industry a short-term one. Consider this situation to put it into perspective: imagine if independent research scientists came up with a cure for a specific form of cancer, but instead of selling it for colossal amounts, they simply gave it free (to the NHS or individuals). This would put many out business and greatly threaten companies in that sector.


This is a very regrettably, pretty close to some real truth.

Success against cancer with modern methods has a truly appalling record if you do some serious research into the cost/benefit ratio.

As for surpressed cures or potential cures, there are any number of them, all usually found in nature.

I posted this as part of another thread, which some of you may have missed, therefore ill repeat it here, because you probably wont find this stuff on the BBC ;

Very few people are aware of the scientific research that has taken place at the chemical and molecular level over the past few years. This clearly indicates that the marijuana plant has some seriously amazing properties, when it comes to how it reacts with the human body.

"the human body actually contains receptors, onto which various chemicals produced naturally by the body attach themselves in a virtual lock and key fashion. These naturally produced human chemicals are so incredibly close in composition to many of the beneficial chemicals found in Cannabinoids, that they are, to all intents and purposes indistinguishable from each other."


The link includes a video (which is well worth anyones time watching IMHO) ;

http://unconventionalrealms.com/food/natural-cancer-fighters


This isnt to say, if you want to cure someone of cancer, get them smoking weed ! DONT!

Its more a case of extracting the various compounds, in the form of oil extracts and testing them.

So why isn't this being done big time? Watch the video for a clearer picture.
Original post by HomoSapiensSap
But a cure would be precisely what large pharmaceutical companies wouldn't want - it would eventually put them out of business as it now makes the industry a short-term one. Consider this situation to put it into perspective: imagine if independent research scientists came up with a cure for a specific form of cancer, but instead of selling it for colossal amounts, they simply gave it free (to the NHS or individuals). This would put many out business and greatly threaten companies in that sector.


Do you understand the difference between the meanings of the words cure and eradicate? Individuals who contract a disease or condition can be cured, even if the disease isn't eradicated, and treating such people would be rather profitable to the drugs company. Given that cancer isn't communicable, people will continue to contract it.
Reply 10
Original post by Mark@UCR
This is a very regrettably, pretty close to some real truth.

Success against cancer with modern methods has a truly appalling record if you do some serious research into the cost/benefit ratio.


Appalling compared with what - how are you judging that? And what do you mean by 'modern methods', are you implying that leeches worked better?

For reference, here's a chart from Cancer Research UK showing how cancer survival rates have improved in England and Wales over a 36 year period. I would say a reasonable achievement considering how complex and varied a disease cancer is. Clearly some cancers have very low survival rates still, but some now have rates approaching 100%.





As for surpressed cures or potential cures, there are any number of them, all usually found in nature.


Leaving aside cannabis which is something of a special case, the problem with 'conspiracy theories' preventing the adoption of magical cancer cures is that they tend to ignore some basics facts about how medical research works.

1. Universities are full of researchers whose main motivations are to discover exiting new things, to publish high impact papers (since this will secure their careers and help them get future funding), and to be the coolest kid at the next conference. They have no motivation to help protect the profits of pharmaceutical companies.

2. The world is full of start-up companies and investors who are constantly searching for the next disruptive technology. Again, they have absolutely no interest in ensuring demand for existing products.

3. Grand conspiracies between larger numbers of people and organisations (with often conflicting goals) are not terribly practical outside of wartime.
(edited 11 years ago)
Reply 11
Original post by Mbob


1. Universities are full of researchers whose main motivations are to discover exiting new things, to publish high impact papers (since this will secure their careers and help them get future funding), and to be the coolest kid at the next conference. They have no motivation to help protect the profits of pharmaceutical companies.

2. The world is full of start-up companies and investors who are constantly searching for the next disruptive technology. Again, they have absolutely no interest in ensuring demand for existing products.

3. Grand conspiracies between larger numbers of people and organisations (with often conflicting goals) are not terribly practical outside of wartime.


Hi there MBob.

Firstly a brief reference to your graph.

Immediately, I dont see too many of those numbers that are anywhere close to 100%

Secondly, could you define what constitutes survival? From all the evidence I have seen this is classified as anyone lasting over 5 years from the time of first diagnosis, which is somewhat misleading don't you think?

Finally, are these figures based upon people who are first diagnosed with the disease, or do they include those many many many cases where the cancer returns?


As to your 3 points.

There can be little doubt that universities and research organisations are full of wonderful, dedicated people who are in turn full of good intentions when it comes to the horrible disease that is cancer. Such membership put their heart and soul into the task. They are heroes to a man/woman.

But who funds these organisations, and more importantly who educates them in the first place?

When it comes to treatment, its all well and good to speak of research and papers, which validate the effectiveness of such treatments, but who carries out the research and trials? Are they independent trials, or are they conducted by the very people who then sell the products?

If you know the answer to that one, then do you consider that to be a safe way to proceed?

As for "conspiracy theories", I fail to see how this enters into this particular discussion. If youve seen the video, you will know that all the facts are laid bare within it. Marijuana as a medical aid was completely outlawed in the US back in the 1930's as a result of direct pressure from Corporate Pharmeceutical concerns, who were clearly trying to steer people away from making their own choices, along with those of the medical community about how disease should be treated. This kind of prohibition is if anything actually getting worse.

The practical implications of this, are that if anyone develops cancer, then the only option at their disposal are treatments that are incredibly expensive to us the taxpayer, or sign this paper and then go and finance alternatives for yourself.

There is nothing wrong whatsoever with attempting to clear the field of Charlattans and snake oil salesmen. Indeed Im all for that.

But where is our protection from the direction this has taken us?

Where is our protection from "licensed" products such as the whole range of pychotropic concoctions and statin drugs, which all independent studies indicate have zero positive effect in the vast majority of cases over a placebo? ( in the case of psychotropic drugs, often they make matters far worse)?

Which surely begs the question as to how they got their license in the first place? Part of the answer has of course can be explained by the fact that in the first place the trials of such products are also conducted by those same companies who then sell the products.

Finally, In a world increasingly dominated by bigger and bigger corporations, whose primary concern is the bottom line, cure is a very bad word. Treatment is a far more beneficial alternatve for such concerns.
Reply 12
Original post by Mark@UCR
Hi there MBob.

Firstly a brief reference to your graph.

Immediately, I dont see too many of those numbers that are anywhere close to 100%

Secondly, could you define what constitutes survival? From all the evidence I have seen this is classified as anyone lasting over 5 years from the time of first diagnosis, which is somewhat misleading don't you think?

Finally, are these figures based upon people who are first diagnosed with the disease, or do they include those many many many cases where the cancer returns?


These particular figures are 10 year survival as it says in the title. 5 Year survival rates are commonly used, although there has been a recent preference for 10 year rates.

There are good reasons for using fixed time-period survival rates, in fact there is no other sensible way of doing it. Everyone dies eventually. And if they live long enough they will get cancer - it's a natural process. So you can't sensibly talk about curing it, only preventing it.



There can be little doubt that universities and research organisations are full of wonderful, dedicated people who are in turn full of good intentions when it comes to the horrible disease that is cancer. Such membership put their heart and soul into the task. They are heroes to a man/woman.

But who funds these organisations, and more importantly who educates them in the first place?



A very large fraction of medical research in the UK is funded by the Government and by charities such as the Wellcome Trust. Some is funded by industry, and this will be declared in the publications. They are largely educated by other academics, although there is some movement in and out of industry.

Beside, you're making an assumption that everyone who is publicly funded is somehow a 'hero' and then everyone who is employed by a company is evil and in-it only for the money. Whereas, actually, people are pretty much the same wherever you go.


When it comes to treatment, its all well and good to speak of research and papers, which validate the effectiveness of such treatments, but who carries out the research and trials? Are they independent trials, or are they conducted by the very people who then sell the products?


Most clinical trials are funded by the companies, otherwise the cost of bringing treatments to market (several hundred million dollars) would be unaffordable. Some are publicly funded.

Although they are funded by companies, they are carried out by scientists and medics. Some degree of trust therefore has to be put in the medical professionals who conduct the trials and the peer review process. Of course these aren't perfect, but they work reasonably well. A bigger concerns is the selective publication of trials which does need to be addressed.



As for "conspiracy theories", I fail to see how this enters into this particular discussion. If youve seen the video, you will know that all the facts are laid bare within it. Marijuana as a medical aid was completely outlawed in the US back in the 1930's as a result of direct pressure from Corporate Pharmeceutical concerns, who were clearly trying to steer people away from making their own choices, along with those of the medical community about how disease should be treated. This kind of prohibition is if anything actually getting worse.


I did say that Marijuana and other illegal drugs are a special case. For one thing it is difficult and costly to obtain a licence to work with them so that research can actually be carried out. You can't extrapolate to other, non illegal substances.

The reason I brought up conspiracy theories was because you said:


As for surpressed cures or potential cures, there are any number of them, all usually found in nature.


which implies a collective conspiracy to prevent cures being brought to market.


Where is our protection from "licensed" products such as the whole range of pychotropic concoctions and statin drugs, which all independent studies indicate have zero positive effect in the vast majority of cases over a placebo? ( in the case of psychotropic drugs, often they make matters far worse)?


I'm not particularly familiar with either of those area, but you can't just cherry pick trials. If you can point to large scale meta analyses which show zero effect then by all means do.



Which surely begs the question as to how they got their license in the first place? Part of the answer has of course can be explained by the fact that in the first place the trials of such products are also conducted by those same companies who then sell the products.


It's not just about licences. In the UK, whether or not a treatment is available on the NHS is decided by NICE - The National Institute for Clinical Excellence. They evaluate the evidence for the efficacy of a treatment and perform a cost/benefit analysis to decide whether or not it should be offered.


The practical implications of this, are that if anyone develops cancer, then the only option at their disposal are treatments that are incredibly expensive to us the taxpayer, or sign this paper and then go and finance alternatives for yourself.


Because of the work of NICE, the reason people opt for a private treatment is so that they can receive a more expensive and less proven treatment on the off-chance it will work, not so they can receive a cheaper one! Unless you are referring to complementary medicine, which would be available on the NHS if it were shown to be effective.



Finally, In a world increasingly dominated by bigger and bigger corporations, whose primary concern is the bottom line, cure is a very bad word. Treatment is a far more beneficial alternatve for such concerns.


You're right in that there is little incentive for a company which produces an expensive treatment to generate an alternative, cheaper treatment. But there is a huge incentive for a rival company to do it - it will benefit their 'bottom line''.
Reply 13
Original post by Mbob
Beside, you're making an assumption that everyone who is publicly funded is somehow a 'hero' and then everyone who is employed by a company is evil and in-it only for the money. Whereas, actually, people are pretty much the same wherever you go.


Yes, I realised when I read my post again that it might have appeared that way. Im not knocking those people either. My argument would actually be that all sides of the cancer treatment sector are essentially working with at least one hand behind their backs. These are all good, dedicated individuals who's effectiveness, by way of their compassion, creativity and industry are all being, to all intents and purposes actively stifled.

I wasnt really suggesting that any of this is inherently evil either. Its the fact that private Corporations have shown themselves repeatedly to be far more concerned with profits than they are about anything else, including cure as opposed to treatment, since their overriding concern, by its very nature is the bottom line.

One of the prime concerns of Corporations is the elimination of competition, as was illustrated with the outlawing of marijuana for medical use.

Therefore, Im wondering if, in the area of human health, leaving all of this to companies who dont have human health itself as the drving concern is the right way to proceed in a developed society?

Access to the wonders of nature in treating virtually any disease is surely an inherent human right.

My argument is that you will never get even close to producing what should be produced by way of effective treatments and yes, cures as long as this is left at the mercy of a system which is predatory by nature.

Whilst changing any of this is not going to be easy, what is far easier nowadays is the ability of people to access the information that will facilitate such change, by allowing them to be aware of this.

This includes all of those people tirelesly working within the field of healthcare, who try so very conscientiously to make a difference.

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