It really does depend on just WHAT you want to do. If you know that, you can look at uni requirements and that can help you choose. For example if you say you want to do medicine, then we'd definitely recommend the science subjects! If you said you wanted to do economics, we'd suggest you do economics! (Though not a mix of economics and business. Economics is enough to get on a business course, but business won't necessarily get you on an economics course)