Ibuprofen (a compound)
pKa = 4.2
M.W of iburofen = 206.29
Intrinsic solubility of ibuprofen at 37 degree celcius = 1 in 25,000
intrinsic solubility in molar concentration at 37 degree celcius= 1.9390^-4 M
the question is:
If a 50mL saturated aqueous solution of ibuprofen prepared at pH7 and 37 degree Celcius is taken orally, how much ibuprofen will be precipitated in the stomach, assuming that the final volume and pH of the fluid in the stomach is 150mL and 1.2 respectively?
I have calculated =
the amount of ibuprofen taken orally to be 6.12 x 10^-3 mol (by using henderson equation and then times the concentration by 50mL)
but then i don't know how to continue the question , can someone help !
thank you very much!
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calculation the solubility and precipitation of a compound watch
- Thread Starter
- 01-11-2015 05:33