Oxygen dissociation curve
Can anyone explain why does the oxygen dissociation curve shift to left in organisms living at high altitude?
Original post by Hayaalderi
Can anyone explain why does the oxygen dissociation curve shift to left in organisms living at high altitude?
At high altitude there is a low partial pressure of oxygen. In response to this, there is a shift to the left at higher altitudes because haemoglobin will have a higher affinity for oxygen. This means it will be able to quickly associate with O2 at a low O2pp/readily saturate itself.
But doesn’t increasing Hb affinity to oxygen makes it difficult to release oxygen to respiring tissues. So how shifting curve to the left is beneficial?
It does , this is the down side of shifting the curve. However, increasing carbon dioixide levels in respiring tissues will also encourage oxygen dissociation
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