If you really are interested in PE go for it and being really good in biology will definitely help you and maybe make your teacher like you more, still, your teacher liking you is not really important. I have a friend who is clumsy and sucks at sports but he is doing pretty good at PE, he says getting A* is immensely hard but passing with a C is super easy.
If drama does not interest you don't choose it because you might get bored.
So choose whichever you feel you'll enjoy the most and not which one you think you'll do better in. If they happen to be the same subject, good, if not then IT DOES NOT MATTER, choose what your heart wants.