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    "Suggest why there are no channels for insulin release across the membrane" [2m]

    Anyone knows how to answer this?

    thanks!
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    (Original post by scarlet-dancer)
    "Suggest why there are no channels for insulin release across the membrane" [2m]

    Anyone knows how to answer this?

    thanks!
    I don't know the context in which you are asking this. If this is concerning the action o insulin, we don't need insulin to go inside the cytosol, because it binds to specific receptors on the cell surface, initiates a cascade of molecular signalling pathways that ultimately regulate glucose. Can you specify more clearly what you are asking about?
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    (Original post by scarlet-dancer)
    "Suggest why there are no channels for insulin release across the membrane" [2m]

    Anyone knows how to answer this?

    thanks!
    Also not exactly sure what you mean. I guess you mean insulin release from beta cells, and why there aren't any membrane channels for insulin to be secreted through?

    If so, remember that insulin and all other hormones are secreted through exocytosis in the ER-Golgi pathway - vesicles and all that so there is no need for channels.

    In fact pretty much all cellular secretion occurs through secretory vesicles from the Golgi, the exception being certain growth factors and cytokines.


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