•
recall a simple description of protein synthesis
•
explain simply how the structure of DNA affects the protein made
•
describe how genetic variants may influence phenotype: a) in coding DNA by altering the activity of a protein: and b) in non-coding DNA by altering how genes are expressed.
•
(HT only) In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
•
(HT only) Students are not expected to know or understand the structure of mRNA, tRNA, or the detailed structure of amino acids or proteins.
•
(HT only) Students should be able to explain how a change in DNA structure may result in a change in the protein synthesised by a gene.
•
(HT only) Proteins are synthesised on ribosomes, according to a template. Carrier molecules bring specific amino acids to add to the growing protein chain in the correct order.
•
(HT only) When the protein chain is complete it folds up to form a unique shape. This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.
•
(HT only) Mutations occur continuously. Most do not alter the protein, or only alter it slightly so that its appearance or function is not changed.
•
(HT only) A few mutations code for an altered protein with a different shape. An enzyme may no longer fit the substrate binding site or a structural protein may lose its strength. (Note: it's not especially clear here but you do need to understand insertions, deletions and the other one which I think is replacements?)
•
(HT only) Not all parts of DNA code for proteins. Non-coding parts of DNA can switch genes on and off, so variations in these areas of DNA may affect how genes are expressed.
•
recall a simple description of protein synthesis
•
explain simply how the structure of DNA affects the protein made
•
describe how genetic variants may influence phenotype: a) in coding DNA by altering the activity of a protein: and b) in non-coding DNA by altering how genes are expressed.
•
(HT only) In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
•
(HT only) Students are not expected to know or understand the structure of mRNA, tRNA, or the detailed structure of amino acids or proteins.
•
(HT only) Students should be able to explain how a change in DNA structure may result in a change in the protein synthesised by a gene.
•
(HT only) Proteins are synthesised on ribosomes, according to a template. Carrier molecules bring specific amino acids to add to the growing protein chain in the correct order.
•
(HT only) When the protein chain is complete it folds up to form a unique shape. This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.
•
(HT only) Mutations occur continuously. Most do not alter the protein, or only alter it slightly so that its appearance or function is not changed.
•
(HT only) A few mutations code for an altered protein with a different shape. An enzyme may no longer fit the substrate binding site or a structural protein may lose its strength. (Note: it's not especially clear here but you do need to understand insertions, deletions and the other one which I think is replacements?)
•
(HT only) Not all parts of DNA code for proteins. Non-coding parts of DNA can switch genes on and off, so variations in these areas of DNA may affect how genes are expressed.
•
recall a simple description of protein synthesis
•
explain simply how the structure of DNA affects the protein made
•
describe how genetic variants may influence phenotype: a) in coding DNA by altering the activity of a protein: and b) in non-coding DNA by altering how genes are expressed.
•
(HT only) In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
•
(HT only) Students are not expected to know or understand the structure of mRNA, tRNA, or the detailed structure of amino acids or proteins.
•
(HT only) Students should be able to explain how a change in DNA structure may result in a change in the protein synthesised by a gene.
•
(HT only) Proteins are synthesised on ribosomes, according to a template. Carrier molecules bring specific amino acids to add to the growing protein chain in the correct order.
•
(HT only) When the protein chain is complete it folds up to form a unique shape. This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.
•
(HT only) Mutations occur continuously. Most do not alter the protein, or only alter it slightly so that its appearance or function is not changed.
•
(HT only) A few mutations code for an altered protein with a different shape. An enzyme may no longer fit the substrate binding site or a structural protein may lose its strength. (Note: it's not especially clear here but you do need to understand insertions, deletions and the other one which I think is replacements?)
•
(HT only) Not all parts of DNA code for proteins. Non-coding parts of DNA can switch genes on and off, so variations in these areas of DNA may affect how genes are expressed.
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