The Wire, Dexter, The Sopranos, Oz, American Dad, The Simpsons (mostly old episodes), South Park, It's Always Sunny in Philadelphia, Misfits, The Walking Dead, Breaking Bad, Malcolm in the Middle, My Name is Earl, and Rome. If I had to choose to have my mind completely wiped of all memory of any of these shows so I could watch them again the top 3 choices would be:
1) Dexter
2) The Wire
3) South Park (maybe always sunny...)
I don't really see what all the fuss is about with Game of Thrones... I'm giving it the benefit of the doubt at the moment because HBO don't generally do crap stuff.