Immune response - a level biology

hello does anyone know what the terms :
clonal selection, clonal expansion and clonal expansion means in the cell mediated response (t lymphocytes). please help! :smile:

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thanks

Reply 1

Suspectthrone59

Clonal selection is when the T lymphocytes that have the complementary receptor to the pathogenic/foreign antigen are identified after they are able to bind to this antigen. Following this, clonal expansion takes place, where these T lymphocytes that have the complementary receptor divide by mitosis and so many copies are made. And then they will differentiate/specialise into T-helper, T-killer and T memory cells.

Reply 2

username1356366

Clonal selection: A theory that explains the functions of cells (lymphocytes) of the immune system in response to specific antigens invading the body.

Clonal expansion: The process that creates the B and T cells, as well as more lymphocytes, from lymphocytes.