I took fluoxetine for about 3 years in my late teens/early 20s and it really benefited me. The side effects were horrendous at first - dizziness, dissociation, loss of appetite, lack of sleep, headaches and feeling sick, although they subsided after 2 or 3 weeks. I was started on 10mg as I was suicidal and at high risk, then increased to 20mg and increased again to 40mg. The important thing to remember is that all drugs work differently for all people, just because fluoxetine has helped me, it doesn't mean every other person with depression will also benefit from taking it. Vice versa with other anti-depressants - someone could find another medication works wonders for them but it could have no affect on me whatsoever.