I think female comedians tend to concentrate on too niche topics.
I hate to generalise, but pretty much every "recognised as good" comedian tends too be a white male. Women comedians tend to focus solely "women issues", similar to how comedians from different nations/cultures tend to focus on their paticular cultures which doesn't appeal very widely.
However, comedians such as Michael McIntyre, Russel Howard, Tim Vine etc... tend to appeal to pretty much everybody. Whether you think they are good comedians is a different matter, but generally, they speak about issues that everybody can relate to. They don't speak about issues that only some women can relate to, or people that have been to a certain country can relate to etc...