Hi there, I've just gotten to the end of 1st year of Chemistry at Imperial College London.
Definitely it is worth having digital notes, and a 4th year researcher who was staying in my halls as a senior told me that an iPad with Apple Pencil is one of the best things a chemistry student can get. But I still don't have one... was saving up and hoping to get one this summer.
When we were new one of the first pieces of software we were introduced to is a software called ChemDraw.
It's extremely intuitive and helps us draw chemical structures fairly easily.
It's nowhere near as fast as hand-drawing, and you will not be able to keep up in lectures if you are using ChemDraw, but it is hugely useful for "neat" notes, powerpoint slides or assignments.
One of the biggest things I learned is my lecture notes technique.
Each of our lectures will have a set of powerpoint slides, and what I have found works best for me is to print out the lecture slides but shrink them down so there is space around each slide, then annotate the slides with different colored pens / highlighters as the lecture is going on.
That way, you do not need to copy down anything on the slides, which will save you from copying structures, but you will have plenty of space to annotate anything else the lecturer says + add anything you learn from recommended reading / tutorials / workshops / revision etc.
I print and use pen and paper but if you have a tablet then you can also use OneNote, Evernote, Apple Freeform or the draw feature in Word or anything similar that works for you.
MAKE SURE TO LEAVE ENOUGH SPACE! I cannot stress this enough. It is not worth trying to save paper / ink / money by printing two slides per side of A4.
You can and should print on both sides of the paper, but only one slide per side of A4!
Just make sure the slide is shrunk down to ~75% (plus or minus a few % depending on the font size on the slide), so there is lots of space.
If you are going to use pen and paper like me then take the time to make files for each module and keep your notes organized.
It came in handy for us - we have open notes exams so I could just take my files into the exam with me and use them to help me answer the problem-solving questions. The disadvantage to open notes exams is that there is a lot less less knowledge recall.
If you need any more tips feel free to DM me!