I am normally very against points hits but this week I had to do it, made 4 transfers and am so glad I did. I took out De Gea, F.Luis, B.Davies and Eriksen and put in Courtois, Jones, Kaboul and Schurle. I didn't want to swap Eriksen but I was late on my transfers so Davies dropped in value. I got 13 more points (then minus the 12 point hit) and can't believe it worked out so well for me. I gained 1 point, I now have all regular starters and I have a better team value (Schurrle went up, Luis and Davies dropped again.)
Like I said, I am against points hits and won't be doing it again but if your players aren't playing, it is worth taking the hit because you will need to get rid of them eventually. Don't take big hits for the sake of it and don't panic buy but if you have non starters, it is defo worth it.