Hey, im in my 3rd year of ITMB at Manchester.
Overall, ITMB at my uni takes a few modules from pure management (i.e. the fundamentals of...) and most of the rest of the modules are designed specially for ITMB with consultation from employers and E-skills. For instance, we learnt the basics of website design (Dreamweaver), java, databases (Access), data mining (Clementine) etc and the rest is pretty much a mixture of theory, and group projects. We had a group project in the 1st and 2nd year, which are full year, and go right through from requirements planning to implementation (the 1st year project was around making a website).
ITMB pretty much gets you prepared for a career in consultancy, and you really do meet a lot of employers, like every week in the 1st and 2nd years. If you take advantage of all the connections (like mentors from companies) its a good way to get ahead, like doing summer placements or a year in industry. Those are hard to get (especially now) but the careeers service at manchester is amazing.
The degree is done slightly differently by some unis, depending on whether they choose to have it as part of the business school or computer science. In general, the school that does the course is where most of the lecturers and admin etc are from.
Id say your choice of uni would depend on the reputation of the department - the business school at manchester is great, so that was important for me. Also, the connections that the school has are also important, like IBM are doing one of our modules this year, which wouldnt happen in all ITMB courses.
Your chances of getting in depend on how full previous years were - the year below me they struggled to get numbers, so made a push the following year to get students in. I got below my offer at manchester, but still got in, so if you like the sound of a uni and their take on the course, go for it. Although a big piece of advice, you wont believe how picky employers are about a levels - they still matter after youve got into uni hehe.
In terms of investment banking, youd probably need an economics degree :P
I hope this helps