Applying to a university with 1 grade below the entry requirement is it worth it

Hey, there's no right or wrong answer here.
Imo, take the shot. Often unis consider "near miss" applicants, plus I am assuming these are predicted grades: who's to say you won't get a A* anyways? A strong personal statement will put you in good stead anyway
Obviously you can have up to five choices, so add one that matches your predicted grades (or just below). What's the worst that can happen? A rejection, which means you lose nothing. You don't apply, there's no chance to get in, you do apply and there's a chance you do. That is how I'd see it personally
Good luck