Am I underselling myself?

Basically I’ve had my university choices set in stone for a while, but now I’ve received my predicted grades I feel like I’m underselling myself - I never expected to be predicted these grades so it’s completely thrown me off kilter.

Context:

I want to study Medicinal Chemistry, and I’m doing the A Levels biology, chemistry, and sociology.

I got 999999888A at GCSE, and I’ve been predicted A*A*A* with an A* at EPQ.

I’m applying to Manchester, Nottingham, Newcastle, Liverpool, and Sheffield. Manchester’s grades are A*AA but the rest are AAB.

I was wondering if anyone had any advice? Would you stick to the same unis or consider applying to somewhere more presitigious?